Tag: Hydroxychloroquine

The Chloroquine Wars Part XIII -A Clockwork Orange Man

Immediately following HCQ’s Trump moment, the media went on an all-out blitz to associate the topic of HCQ with a sense of fear. Fear of Trump, fear of death, fear of incompetence, fear of opposing scientific authorities, fear of using medicine needed by somebody else, and fear of the unknown. And the campaign of fear didn’t stop there.

Read More »

Clinical outcomes of patients with mild COVID-19 following treatment with hydroxychloroquine in an outpatient setting

Our investigation of a large national cohort appears to support early administration (within the first 3 to 7 days of COVID-19 diagnosis) of HCQ in mild COVID-19 disease in an outpatient setting for reducing hospitalizations and deaths without any serious adverse HCQ-related effects.
If this finding is confirmed in future clinical trials, HCQ as a cheap and available drug may still play a role in a specific population with respect to reducing COVID-19 burden, particularly in resource-poor countries.

Read More »

Association of Italian Doctors successfully treats COVID patients with vitamin D and hydroxychloroquine

From an ingenious intuition of the founder, Mauro Rango, an Italian living in the Mauritius Islands. There, the Coronavirus was quickly eradicated in the beginning, with drugs that we have known for decades, such as Azithromycin, Hydroxychloroquine or Cortisone, while in Italy people died like flies. How was it possible that in Africa, where health care is not as advanced as in Italy, such marvellous results were achieved, while in Italy the spread of the disease could not be contained?

Read More »

Timing and dosing are the key to HCQ + AZ treatment in elderly Covid-19 patients

Antiviral therapy is only of interest during the early and intermediate viral phase when the virus is present and replicates, and is of no use during the late inflammatory phase (cytokine storm). Most therapeutic trials, unfortunately, have been carried out in hospitalized patients, which is to say probably often too late, because the patients are in the early inflammatory phase.

Read More »

The Chloroquine Wars Part VI – The Simple Logic of the Hydroxychloroquine Hypothesis

The Hydroxychloroquine Hypothesis: That there is some appropriate dosage of hydroxychloroquine, alone or in some combination with other medication, that successfully prevents some COVID-19 cases (PrEP/PEP) or treats some COVID-19 sufferers (Early/Late/Critical).
Remaining entirely unblemished after a year of trials and observations, the current evidence in favor of the Primary HCQ Hypothesis fully validates the HCQ Hypothesis. The logic is so simple that it almost feels like your livelihood would have to be on the line to deny it.

Read More »

Structural basis of anti-SARS-CoV-2 activity of hydroxychloroquine: specific binding to NTD/CTD and disruption of LLPS of N protein

In this study, by use of DIC microscopy and NMR spectroscopy, for the first time we have decoded that HCQ specifically binds to both N-terminal domain (NTD) and C-terminal domain (CTD) of SARS-CoV-2 nucleocapsid (N) protein to inhibit their interactions with nucleic acids (NAs), as well as to disrupt its NA-induced liquid-liquid phase separation (LLPS) essential for the viral life cycle including the package of gRNA and N protein into new virions.

Read More »

The Chloroquine Wars Part IV

Why then does the pharmaceutical industry and its promoters insist on conducting RCTs before something is accepted as true? RCTs take substantial amounts of time and significant resources to conduct. This creates a barrier to entry, especially for inexpensive solutions to medical problems. In other words, the myth that RCTs are some necessary “gold standard” is a deception that, along with regulatory agency, prevent any possibility for simpler and less expensive (less profitable) medical solutions to gain traction.

Read More »

We learn that 30 million Indians have been cured by ivermectin and hydroxychloroquine, but donkeys everywhere, like Véran or Wargon, claim that there is no cure…

India has conquered the disease with hydroxychloroquine and ivermectin, uses a traditional vaccine, exports experimental vaccines for these idiotic Westerners … There are 1,230 deaths per million inhabitants over 65 (six times less than in France). If we had listened to Raoult and followed the Indian model, today we would have 500 cases of covid per day and 75,000 fewer deaths …

Read More »

The Chloroquine Wars Part III

If the argument rests on “RCTs as the gold standard”, there is little doubt that the evidence dramatically favors using HCQ as a standard early stage therapeutic! But it is reasonable to assess the quality of all the evidence to reach beyond gold for the ultimate and supreme standards of scientific evidence. That too we plan to present in future articles.

Read More »

Professor Risch Responds to Dr Rushworth over Hydroxychloroquine Post

“As a clinician, you should know that Covid-19 outpatient disease is viral replication, vs hospitalized disease which is florid pneumonia. These are absolutely different conditions and studies of the treatment of one cannot be extrapolated to the treatment of the other.
This massive body of evidence, summarized by the Cochrane Library, demonstrates that well-conducted hydroxychloroquine observational studies on average, produce very similar associations as the corresponding RCTs.

Read More »

The Chloroquine Wars: Part I

A famous infectious diseases specialist from France, Dr. Didier Raoult, devised treatments for the bacterial infections that cause Q fever and Whipple’s disease. If all that weren’t enough, hydroxychloroquine has anti-thrombotic properties, meaning it reduces blood clotting for patients suffering excessive clotting. It even inhibits autophagy (cellular self-destruction) setting up hydroxychloroquine for research as a unique cancer medication. No other medicine discovered, isolated, or engineered does all of these things. Most importantly during the recent pandemic, hydroxychloroquine, like quinine, also demonstrates antiviral activity. In short, hydroxychloroquine is a gift from nature—one of the most broadly effective and repurposed drugs in the history of medicine. Billions of doses of hydroxychloroquine are distributed annually, and the WHO includes it in its list of essential medicines.

Read More »

Killing the cure: The strange war against hydroxychloroquine

The UK has had the ignominious triumph of having one of the world’s highest death rates. Some see the solution in continuing lockdowns, more testing and ultimately the vaccine. We argue that the solution lies in medical treatments, such as hydroxychloroquine or ivermectin rather than in vaccination. But hydroxychloroquine was ruled out as a potential treatment for covid19 quite early on. This is despite the fact that, when used correctly, it is a highly efficacious treatment. Had it been readily available as a prophylactic or early stage treatment we would need neither lockdowns nor vaccinations and dramatically fewer people would have died. However this didn’t happen. Here we intend to explore why.

Read More »

Facebook Suspends Craig Kelly For Posts Citing Medical Professionals

“The effect of censoring debate on these early treatments could have possibly been responsible for the death of hundreds of thousands of people.
So, where we should have been having more open debate and more free debate, shutting down debate is likely to have killed people. Not just one or two people, but probably hundreds of thousands. This is why throughout the last 250 years people have said free speech is so important. This is why people have said, ‘I may not agree with what you say but I’ll fight to my death your right to say it.’”

Read More »

Follow the Money: Hydroxychloroquine vs. the “Vaccine”

With a medical establishment seemingly hell-bent on making billions of dollars instead of providing a viable, effective, low-cost pre-hospital treatment, Dr. Zelenko suffered the fate so many have experience since Nov. 4 of 2020. The life-saving information he shared on Twitter was cut off because they terminated his account without warning.

Read More »

CANADA: Trudeau government attempts to downplay hydroxychloroquine purchase

An email from Prime Minister Trudeau’s director of policy and cabinet affairs, Rick Theis, to Trudeau’s lead speechwriter, Astrid Krizus, about the ordering of pandemic supplies shows that the writer was suggested to make no mention of the Government of Canada’s purchase of hydroxychloroquine alongside other supplies, when preparing an official statement.

Read More »

Covid-19: Ivermectin treatment successes already a victim of dishonest attacks

Ivermectin: There is a technique of discrediting which is all the rage, always to manipulate: to criticize the form, to make forget the main one: the result. Virtually all of the studies cited by the paper are 95% criticized on form and not on substance, leading to the conclusion, despite results that even a 5-year-old would find obvious, that there is insufficient evidence. If, one day, public domain Ivermectin becomes THE drug against Sars-Cov-2, that will result in billions of losses for the global pharmaceutical industry.

Read More »

Hydroxychloroquine & Covid-19: India and France, a cruel comparison

With such a rate of contamination, we are faced with a scenario of collective quasi-immunity managed with a broad prescription of early and prophylactic treatment based on hydroxychloroquine. With a contamination rate of 56%, mortality is 549 people per million inhabitants. Last December, the Institut Pasteur estimated the rate of the French population to be contaminated at 11.3% [1]. Mortality in France is 1200 [2] people per million inhabitants. The population of Delhi is five times more contaminated with mortality more than two times lower compared to France. The case fatality rate with early treatment in Delhi, which is 0.1%, is close to the rate estimated by Professor Raoult in the case of early treatment.

Read More »