Category: Solutions

Timing and dosing are the key to HCQ + AZ treatment in elderly Covid-19 patients

Antiviral therapy is only of interest during the early and intermediate viral phase when the virus is present and replicates, and is of no use during the late inflammatory phase (cytokine storm). Most therapeutic trials, unfortunately, have been carried out in hospitalized patients, which is to say probably often too late, because the patients are in the early inflammatory phase.

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The Chloroquine Wars Part VI – The Simple Logic of the Hydroxychloroquine Hypothesis

The Hydroxychloroquine Hypothesis: That there is some appropriate dosage of hydroxychloroquine, alone or in some combination with other medication, that successfully prevents some COVID-19 cases (PrEP/PEP) or treats some COVID-19 sufferers (Early/Late/Critical).
Remaining entirely unblemished after a year of trials and observations, the current evidence in favor of the Primary HCQ Hypothesis fully validates the HCQ Hypothesis. The logic is so simple that it almost feels like your livelihood would have to be on the line to deny it.

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Structural basis of anti-SARS-CoV-2 activity of hydroxychloroquine: specific binding to NTD/CTD and disruption of LLPS of N protein

In this study, by use of DIC microscopy and NMR spectroscopy, for the first time we have decoded that HCQ specifically binds to both N-terminal domain (NTD) and C-terminal domain (CTD) of SARS-CoV-2 nucleocapsid (N) protein to inhibit their interactions with nucleic acids (NAs), as well as to disrupt its NA-induced liquid-liquid phase separation (LLPS) essential for the viral life cycle including the package of gRNA and N protein into new virions.

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Ivermectin: How a nurse saved herself from her battle with COVID-19

The doctor refused and put her on other medicines. Patti’s condition deteriorated further, and when she returned a second time to the ER, she was again refused ivermectin and sent home on oxygen. When her condition failed to improve over several weeks, she finally obtained a prescription for ivermectin from a doctor and within days, she began to recover.

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Censorship Kills: The Shunning of a COVID Therapeutic

The science shows that ivermectin works. Over 40 randomized trials and observational studies from around the world attest to its efficacy against the novel coronavirus. Meta-analyses by four separate research groups, including ours, found an average reduction in mortality of between 68%-75%. And 10 of 13 randomized controlled trials found statistically significant reductions in time to viral clearance, an effect not associated with any other COVID-19 therapeutic. Furthermore, ivermectin has an unparalleled safety record and low cost, which should negate any fears or resistance to immediate adoption.

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The Chloroquine Wars Part IV

Why then does the pharmaceutical industry and its promoters insist on conducting RCTs before something is accepted as true? RCTs take substantial amounts of time and significant resources to conduct. This creates a barrier to entry, especially for inexpensive solutions to medical problems. In other words, the myth that RCTs are some necessary “gold standard” is a deception that, along with regulatory agency, prevent any possibility for simpler and less expensive (less profitable) medical solutions to gain traction.

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We learn that 30 million Indians have been cured by ivermectin and hydroxychloroquine, but donkeys everywhere, like Véran or Wargon, claim that there is no cure…

India has conquered the disease with hydroxychloroquine and ivermectin, uses a traditional vaccine, exports experimental vaccines for these idiotic Westerners … There are 1,230 deaths per million inhabitants over 65 (six times less than in France). If we had listened to Raoult and followed the Indian model, today we would have 500 cases of covid per day and 75,000 fewer deaths …

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The Chloroquine Wars Part III

If the argument rests on “RCTs as the gold standard”, there is little doubt that the evidence dramatically favors using HCQ as a standard early stage therapeutic! But it is reasonable to assess the quality of all the evidence to reach beyond gold for the ultimate and supreme standards of scientific evidence. That too we plan to present in future articles.

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Professor Risch Responds to Dr Rushworth over Hydroxychloroquine Post

“As a clinician, you should know that Covid-19 outpatient disease is viral replication, vs hospitalized disease which is florid pneumonia. These are absolutely different conditions and studies of the treatment of one cannot be extrapolated to the treatment of the other.
This massive body of evidence, summarized by the Cochrane Library, demonstrates that well-conducted hydroxychloroquine observational studies on average, produce very similar associations as the corresponding RCTs.

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The Chloroquine Wars Part II

On face, it certainly appears that complete silence in the public sphere about hydroxychloroquine’s potential was coordinated by powerful media forces.

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The Chloroquine Wars: Part I

A famous infectious diseases specialist from France, Dr. Didier Raoult, devised treatments for the bacterial infections that cause Q fever and Whipple’s disease. If all that weren’t enough, hydroxychloroquine has anti-thrombotic properties, meaning it reduces blood clotting for patients suffering excessive clotting. It even inhibits autophagy (cellular self-destruction) setting up hydroxychloroquine for research as a unique cancer medication. No other medicine discovered, isolated, or engineered does all of these things. Most importantly during the recent pandemic, hydroxychloroquine, like quinine, also demonstrates antiviral activity. In short, hydroxychloroquine is a gift from nature—one of the most broadly effective and repurposed drugs in the history of medicine. Billions of doses of hydroxychloroquine are distributed annually, and the WHO includes it in its list of essential medicines.

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Drug delay dismay – Jamaican doctors blame health ministry for slow approach to importing Ivermectin

“Potent anti-inflammatory and anti-viral properties have now been demonstrated against SARS CoV-2. A significant body of peer-reviewed evidence has now emerged pointing to the fact that Ivermectin may decrease the case count and mortality rates when used as a prophylactic agent, and when used in the treatment of all stages of COVID-19. The safety profile of this drug is well demonstrated after 40 years of clinical use,” the MAJ president said.

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UK: Lice and scabies drug, Ivermectin, could cut Covid deaths by up to 75%, research suggests

More than 30 trials across the world found that ivermectin causes ‘repeated, consistent, large magnitude improvements in clinical outcomes’ at all stages of the disease. The peer-reviewed study, to be published in the US journal Frontiers of Pharmacology, says the evidence is so strong that the drug – used to treat head lice and scabies – should become a standard therapy everywhere, so hastening the global recovery.

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Killing the cure: The strange war against hydroxychloroquine

The UK has had the ignominious triumph of having one of the world’s highest death rates. Some see the solution in continuing lockdowns, more testing and ultimately the vaccine. We argue that the solution lies in medical treatments, such as hydroxychloroquine or ivermectin rather than in vaccination. But hydroxychloroquine was ruled out as a potential treatment for covid19 quite early on. This is despite the fact that, when used correctly, it is a highly efficacious treatment. Had it been readily available as a prophylactic or early stage treatment we would need neither lockdowns nor vaccinations and dramatically fewer people would have died. However this didn’t happen. Here we intend to explore why.

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Facebook Suspends Craig Kelly For Posts Citing Medical Professionals

“The effect of censoring debate on these early treatments could have possibly been responsible for the death of hundreds of thousands of people.
So, where we should have been having more open debate and more free debate, shutting down debate is likely to have killed people. Not just one or two people, but probably hundreds of thousands. This is why throughout the last 250 years people have said free speech is so important. This is why people have said, ‘I may not agree with what you say but I’ll fight to my death your right to say it.’”

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Role of ivermectin in the prevention of SARS-CoV-2 infection among healthcare workers in India: A matched case-control study

We conclude that two-dose ivermectin prophylaxis at a dose of 300 μg/kg body weight with a gap of 72 hours was associated with a 73% reduction of SARS-CoV-2 infection among HCWs in the following one month. Chemoprophylaxis has relevance in the containment of pandemic. This is an intervention worth replicating at other centers until a vaccine is widely available.

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Follow the Money: Hydroxychloroquine vs. the “Vaccine”

With a medical establishment seemingly hell-bent on making billions of dollars instead of providing a viable, effective, low-cost pre-hospital treatment, Dr. Zelenko suffered the fate so many have experience since Nov. 4 of 2020. The life-saving information he shared on Twitter was cut off because they terminated his account without warning.

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CANADA: Trudeau government attempts to downplay hydroxychloroquine purchase

An email from Prime Minister Trudeau’s director of policy and cabinet affairs, Rick Theis, to Trudeau’s lead speechwriter, Astrid Krizus, about the ordering of pandemic supplies shows that the writer was suggested to make no mention of the Government of Canada’s purchase of hydroxychloroquine alongside other supplies, when preparing an official statement.

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