The Palmer Foundation
Source: Science Direct Abstract Background In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is used in the treatment of COVID-19. Methods We retrospectively report on 1061 SARS-CoV-2 positive tested patients treated with HCQ (200 mg three times daily for ten days) + AZ (500 mg on day 1 followed by 250 mg daily for the next four days) for […]
Source: MedRxiv Background Effective therapies are urgently needed for the SARS-CoV-2 pandemic. Chloroquine has been proved to have antiviral effect against coronavirus in vitro. In this study, we aimed to assess the efficacy and safety of chloroquine with different doses in COVID-19. Method In this multicenter prospective observational study, we enrolled patients older than 18 […]
Source: The Jerusalem Post Annalisa Chiusolo shows how the drug hydroxychloroquine could make people immune to virus COVID-19 damages the hemoglobin, impairing the ability of red blood cells to transport oxygen throughout the body, compromising the lungs and resulting in Acute Respiratory Distress Syndrome (ARDS), Italian pharmacology scholar Annalisa Chiusolo explained to The Jerusalem Post. If her thesis […]
Source: MedRxiv This study provides the first in vivo evidence that zinc sulfate in combination with hydroxychloroquine may play a role in therapeutic management for COVID-19. Philip Carlucci, Tania Ahuja, Christopher M Petrilli, Harish Rajagopalan, Simon Jones, Joseph Rahimian Background: COVID-19 has rapidly emerged as a pandemic infection that has caused significant mortality and economic losses. Potential therapies and means of prophylaxis against COVID-19 are urgently […]
Source: India Today As some Western studies found hydroxychloroquine ineffective as a potential Covid-19 therapy, a new Chinese research has reported that the anti-malarial drug brought down mortality rates significantly among critical coronavirus patients. The latest preprint study — which means it’s not yet peer-reviewed — is based on the clinical analysis of 568 Covid-19 […]
Source: MedRxiv Abstract Importance: Coronavirus disease 2019 (COVID-19) is a pandemic with no specific drugs and high mortality. The most urgent thing is to find effective treatments. Objective: To determine whether hydroxychloroquine application may be associated with a decreased risk of death in critically ill COVID-19 patients and what is potential mechanism. Design, Setting and […]
Dr. Zelenko, during his interview with Steve Bannon, said his protocol provides a 95% reduction in death, that France used a similar protocol and had an 88% reduction in death.
The records review reported outcomes where hydroxychloroquine alone was provided to our sickest COVID-19 patients. The Veterans who received hydroxychloroquine were at highest risk prior to receiving the medication. Robert L. Wilkie – The Secretary of Veteran Affairs, Washington In a letter sent to veterans organizations, Wilkie clarified that a recent analysis of those hospitalized in […]
Source: (CBSNewYork) ROSLYN, N.Y. – One New York doctor claims to have kept hundreds of coronavirus patients out of the hospital with a cocktail of medications. It’s been criticized as unproven, but a major hospital in New York takes it seriously, and is launching a clinical trial based on the treatment, reports CBS2’s Carolyn Gusoff. In the […]
SOURCE: The Sun UKDOCTORS in the US have claimed that a now controversial malaria drug does help patients diagnosed with the coronavirus. They say medics should start giving the drug to patients after 91.7 per cent showed improvements on the drug. A report published by the Association of American Physicians and Surgeons (AAPS) stated patients […]
Source: MedRxiv Importance: Coronavirus disease 2019 (COVID-19) is a pandemic with no specific drugs and high mortality. The most urgent thing is to find effective treatments. Objective: To determine whether hydroxychloroquine application may be associated with a decreased risk of death in critically ill COVID-19 patients and what is potential mechanism. Design, Setting and Patients: […]
Source: medRxiv View ORCID Profile Mohammad Ali Ashraf, Nasim Shokouhi, Elham Shirali, Fateme Davari-tanha, Omeed Memar, View ORCID Profile Alireza Kamalipour, Ayein Azarnoush, Avin Mabadi, Adele Ossareh, Milad Sanginabadi, Talat Mokhtari Azad, Leila Aghaghazvini, Sara Ghaderkhani, Tahereh Poordast, Alieh Pourdast, Pershang Nazemi doi: https://doi.org/10.1101/2020.04.20.20072421 Abstract Info/History Metrics Preview PDF Abstract Purpose There is a growing need for information regarding the recent coronavirus disease of 2019 (Covid-19). We present a comprehensive report of Covid-19 […]
Response to Magagnoli, MedRxiv, 2020 Matthieu MILLION1,2, Yanis ROUSSEL1,2, Didier RAOULT1,2 1 IHU-Méditerranée Infection, Marseille, France 2 Aix Marseille Univ, IRD, AP-HM, MEPHI, Marseille, France In the current period, it seems that passion dominates rigorous and balanced scientific analysis and may lead to scientific misconduct. The article by Magagnoli et al. (Magagnoli, 2020) is an […]
Every patient who is hospitalised with COVID-19 in Australia will be asked to participate in a clinical trial that aims to assess whether two potential drug treatments for coronavirus are effective. The major clinical trial, known as the ASCOT study, will involve every hospital around the country that is caring for COVID-19 patients. Patients who […]
Source: iltempoInterview with the Italian researcher Andrea Savarino reveals research on 211 people, showing how prophylaxis with hydroxychloroquine prevents the infection of Covid-19. The result of a COVID-19 prophylaxis experiment in people exposed to coronavirus positive individuals has been published in the journal International Journal of Antimicrobial Agents, the official body of the International Society […]
This study focuses on anti-malarial drugs like hydroxychloroquine, which have been seen as the most used treatment for COVID-19
The U.S. Food and Drug Administration and Novartis have reached an agreement to permit the Swiss company to go ahead with a clinical trial of the anti-malaria drug hydroxychloroquine for those who have contracted the coronavirus. Novartis announced it will start enrollment for the third phase of the clinical trial for some 440 patients within the next […]
Sermo’s Barometer studies have polled over 20,000 physicians globally regarding COVID-19 New York – April 17, 2020 – Hydroxychloroquine, a widely available and inexpensive drug initially used for malaria as well as lupus and rheumatoid arthritis, has been the subject of intense medical and political debate as researchers work quickly to determine its ability to fight […]
A healthcare analytics firm hopes to steer providers to the best therapies for COVID-19 patients of varying ages and medical problems by breaking down patient responses to four different treatments. “Because it’s real, live data streaming in, what individual physicians or hospitals or public policy individuals can do is be able to make judgments in their […]
SOURCE: Covexit The advanced copy of a new study, by Rodrigo Barbosa Esper M.D., Ph.D. and collaborators has just been circulated. The study analyzes the effects of hydroxychloroquine and azithromycin treatment, via telemedicine, can reduce the need for hospitalization. This is the first of several articles that will be published in relation to the study […]
The benefits of hydroxychloroquine being investigated in multi-site clinical trial launching in April Researchers are investigating whether hydroxychloroquine – a commonly used anti-malarial and autoimmune drug – can prevent COVID-19. A multi-site clinical trial, led by the University of Washington Department of Global Health/International Clinical Research Center (ICRC) in collaboration with NYU Grossman School of […]
Percentage of New York Physicians Who Have Used Hydroxychloroquine Nearly Doubled, Italian and French Physicians Jumped 30% Points + Over 2 Weeks Week over week increases in usage Percentage of physicians in New York who have used Hydroxychloroquine nearly doubled since Wave 1 week of March 25 (23% to 40% to 43% wave over wave). […]
Source: Washington Examiner Watch the excerpt: South Dakota will be the first U.S. state to hold a statewide trial for hydroxychloroquine as a possible treatment of the coronavirus. Gov. Kristi Noem announced on Monday that the state health department and every major hospital would take part in a clinical trial to treat COVID-19 patients and those who […]
Japan’s Gunma University Hospital is planning what is roughly positioned as a mid-stage clinical trial covering hydroxychloroquine and other medicines for the novel virus disease. According to the university, it is planning to conduct “specified clinical research” (tokutei rinsho kenkyu; clinical research on unapproved drugs/indications or clinical research funded by drug maker) on multiple drugs […]
Given the speed of evolution of the epidemic and the permanent information needs of the scientific community, combined with the difficulty of travel, the IHU has decided to put online the submitted articles (preprint), as have already started to do the sites but which in the current situation have deadlines too important to be compatible […]
Source: Science Direct PhilippeGautretab1Jean-ChristopheLagierac1PhilippeParolaabVan ThuanHoangabdLineMeddebaJacquesSevestreaMorganeMailheaBarbaraDoudieraCamilleAubryaSophieAmraneaPisethSengaMarieHocquartaCaroleEldinabJulieFinanceeVera EstevesVieiraaHervé TissotTissot-DupontacStéphaneHonoréfgAndreasSteinacMatthieuMillionacPhilippeColsonacBernardLa ScolaacVéroniqueVeithAlexisJacquieriJean-ClaudeDeharojMichelDrancourtacPierre EdouardFournierabJean-MarcRolainacPhilippeBrouquiacDidierRaoultac aIHU-Méditerranée Infection, Marseille, France bAix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France cAix Marseille Univ, IRD, APHM, MEPHI, Marseille, France dThai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam eAssistance Publique de Marseille, Hôpital Nord, Explorations Fonctionnelles Respiratories, Aix Marseille Université, France fService […]
Professor Didier Raoult has reserved for the President of the Republic the exclusivity of his follow-up study on 1,061 patients passed through his services. Virologic healing was achieved in 973 patients in 10 days. The chloroquine debate is continuing. This is an explosive movement that made Thursday Emmanuel Macron to meet the controversial Professor Didier Raoult, home to Marseille, […]
Data from week two of largest ongoing international market research study on COVID-19 New York, New York – April 8, 2020 – Week two data of the Barometer study from 5,000 physicians in 30 countries conducted by Sermo reveals the emergence of treatment patterns. Sermo, the largest global healthcare polling company and social platform for physicians, has published unrestricted access […]
Hydroxychloroquine reduces time to clinical recovery when treating COVID-19 disease patients: The accelerating debate about the clinical benefit of treating COVID-19 disease patients with hydroxychloroquine became a little bit clearer with a new study. Previous studies have indicated that chloroquine (CQ) shows antagonism against COVID-19 in vitro. As a derivative of CQ, hydroxychloroquine (HCQ) is reported […]
Source: Brasil Sem Medo Paolo Zanotto, virologist at the University of Sao Paulo, says that the use of hydroxychloroquine is the most effective method to save thousands of lives and prevent a historic tragedy. Virologist Paolo Zanotto, professor in the Department of Microbiology at USP, says that the use of hydroxychloroquine in coronavirus patients is […]
SOURCE: Detroit Metro Times After being accused of “banning” the use of a potential coronavirus drug, Michigan is now leading the nation’s largest study on whether hydroxychloroquine can be used to treat COVID-19. Gov. Gretchen Whitmer was asked about the new study of the drug, announced by Henry Ford Health System on Thursday, during a coronavirus town […]
A patient at the Amiens University Hospital who presented symptoms of the Covid-19 coronavirus was administered hydroxychloroquine-based treatment.
A drug combo already used against HIV. A malaria treatment first tested during World War II. A new antiviral whose promise against Ebola fizzled last year. Could any of these drugs hold the key to saving coronavirus disease 2019 (COVID-19) patients from serious harm or death? On Friday, the World Health Organization (WHO) announced a […]
Source medRxiv Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Zhaowei Chen, View ORCID ProfileJijia Hu, Zongwei Zhang, Shan Jiang, Shoumeng Han, Dandan Yan, Ruhong Zhuang, Ben Hu, View ORCID ProfileZhan Zhangdoi: https://doi.org/10.1101/2020.03.22.20040758This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice. Abstract Aims: Studies […]
Source: National Library of Medicine Conclusion: Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin. Hydroxychloroquine and Azithromycin as a Treatment of COVID-19: Results of an Open-Label Non-Randomized Clinical Trial Philippe Gautret 1, Jean-Christophe Lagier 2, Philippe Parola 1, Van Thuan Hoang 3, Line Meddeb 4, Morgane […]
A University of Queensland team is among more than 35 research groups around the world desperately working to find a vaccine for COVID-19. It comes as Clive Palmer has been revealed as the mystery man behind a $1 million donation towards research. Read the original article here: https://www.couriermail.com.au/subscribe/news/1/?sourceCode=CMWEB_WRE170_a&dest=https%3A%2F%2Fwww.couriermail.com.au%2Flifestyle%2Fhealth%2Fthe-new-treatments-that-could-beat-covid19-coronavirus%2
To increase the effectiveness of treatments and results, researchers need to give greater focus, when designing trials and when extrapolating from them.
Kwon Jun-wook, deputy head of the Korea Centers for Disease Control and Prevention, said Thursday at a regular press briefing the recommendations come from multiple groups, and that the government is ready to apply the recommendations to patients “where necessary,” The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, Korean Society of Pediatric […]
An initial Chinese study, published in Clinical Infectious Diseases: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection. Hydroxychloroquine shares the same mechanism of action as chloroquine, but its more tolerable safety profile makes it the preferred […]
Doctors of subordinate Moscow medical institutions are invited to participate in the study of the drug for the prevention of COVID-19. A medicine called hydroxychloroquine is used for rheumatoid arthritis and malaria. Moscow doctors are invited to take part in the study of hydroxychloroquine for the prevention of coronavirus on the site doc-covid.ru. It was created on […]