French research team Colson, Rolain, Raoult propose the following in the International Journal of Antimicrobial Agents:
In the current episode of novel coronavirus (SARS-CoV-2) emergence , we find a spectacular example of possible repositioning of drugs, particularly chloroquine. We had 20 years ago proposed to systematically test chloroquine in viral infections because it had been shown to be effective in vitro against a broad range of viruses [3,4]. This drug has multiple activities, one of which is to alkalise the phagolysosome, which hampers the low-pH-dependent steps of viral replication, including fusion and uncoating.
Read the original article here: https://www.sciencedirect.com/science/article/pii